The Bureau of South and Central Asian Affairs conducts U.S. foreign relations with countries in the region of South and Central Asia. This bureau directs, coordinates and supervises diplomatic activities within this region, including consular and administrative management issues.
- SCA Front Office (SCA/FO): directs, coordinates, and supervises diplomatic activities within the South and Central Asian countries, including consular and administrative management issues.
- Office of Central Asia (SCA/CEN): informs policy and coordinates with U.S. Missions in Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan.
- Office of INSB (SCA/INSB): informs policy and coordinates with U.S. Missions in India, Nepal, Sri Lanka, Bhutan, and Maldives.
- Afghanistan Desk (SCA/A): is responsible for U.S. policy toward Afghanistan, and liaises with the U.S. Embassy in Afghanistan.
- India Desk (SCA/I): is responsible for U.S. policy toward India, and liaises with the U.S. Embassy in India.
- Pakistan Desk (SCA/P): is responsible for U.S. policy toward Pakistan, and liaises with the U.S. Embassy in Pakistan.
- Office of Press and Public Diplomacy (SCA/PPD): integrates public diplomacy planning, programming, and evaluation into the overall work of the SCA Bureau.
- Office of Regional Affairs (SCA/RA): provides the Bureau of South and Central Asia with expertise on and coordination of a broad spectrum of functional, global, and trans-border issues pertaining to the South and Central Asian region.